Phenanthrenes and derivatives

Polycyclic aromatic hydrocarbon compounds that consist of fourteen carbon atoms and ten hydrogen atoms fused into three benzene rings. Includes compounds that are derived from phenanthrenes.

Search Within Results

256 – 270 of 290 results

256

Medchemexpress LLC Aristolochic acid C | 4849-90-5 | 327.25 | 1 MG

Aristolochic acid C is a derivative of Aristolochic acid, which functions as a phospholipase A2 (PLA2) inhibitor. This inhibition disrupts cortical microtubule arrays and root growth in *Arabidopsis*.

Purity: 99.77%
Appearance: solid
Color: light yellow to orange
Solubility in vitro: DMSO : 125 mg/mL (381.97 mM; needs ultrasonic)
Shipping: room temperature in continental US; may vary elsewhere
Storage: 4°C, protected from light
Storage in solvent: -80°C, 6 months; -20°C, 1 month (protected from light)
In vivo dissolution protocol: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (solubility: ≥ 2.08 mg/mL (6.36 mM); clear solution)

Pricing & Availability

257

Medchemexpress LLC MI-217 100 mg

MI-217 100MG

Pricing & Availability

258

Medchemexpress LLC 2H-1-benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-(3R,4S) | 1213777-80-0 | 99.9% | 348.39 g/mol | C22H20O4 | 5 MG

Triphen diol is a phenol diol small-molecule research compound (CAS 1213777-80-0) reported to induce apoptosis and inhibit proliferation in pancreatic cancer models. It has molecular formula C22H20O4, molecular weight 348.39 g/mol, and is supplied with high reported purity for use in in vitro and in vivo studies. Solubility and storage guidance is provided to support experimental workflows.

Phenol diol small-molecule with reported anticancer activity.
Demonstrated apoptosis induction and antiproliferative effects in pancreatic cancer cell lines.
High reported purity suitable for biological assays.
Soluble in DMSO at concentrations useful for stock preparations.
Reported in vivo formulation options that yield clear solutions at ≥2.5 mg/mL.
Storage recommendations provided to maintain stability during short- and long-term storage.

Pricing & Availability

259

Ambeed 6 12Dibromochrysene

6,12-Dibromochrysene, 131222-99-6, 97%

Pricing & Availability

260

TARGETMOL CHEMICALS INC HYPERICIN 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo. purity: 99%

Pricing & Availability

261

Medchemexpress LLC PROTAC BCR-ABL1 ligand 1 | 2489876-34-6 | 99.17% | 50 MG

PROTAC BCR-ABL1 ligand 1, also known as compound GMB-475, is a PROTAC ligand that allosterically targets the BCR-ABL1 protein. It functions by recruiting the E3 ligase Von Hippel-Lindau, which leads to the ubiquitination and subsequent degradation of BCR-ABL1.

Allosterically targets the BCR-ABL1 protein.
Recruits the E3 ligase Von Hippel-Lindau.
Induces ubiquitination and subsequent degradation of BCR-ABL1.
Inhibits cell proliferation with IC50 values of 1.11 μM for WT cells, 1.98 μM for T315I cells, and 0.37 μM for G250E cells.
Induces the degradation of c-ABL1.
Inhibits downstream signaling through the STAT5 pathway in K562 and Ba/F3 cells.