Phenanthrenes and derivatives
eMolecules 1705-85-7 | 6-Methyl Chrysene | Toronto Research Chemicals | MFCD00215920 | 242.321 | C19H14 | 95.000 | Cc1cc2c3ccccc3ccc2c2ccccc12 | 100mg | 601597882
6-Methyl Chrysene | Toronto Research Chemicals | 1705-85-7 | MFCD00215920 | 242.321 | C19H14 | 95.000 | Cc1cc2c3ccccc3ccc2c2ccccc12 | 100mg | 601597882
Medchemexpress LLC Chrysen-6-amine | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 10 MG
6-Aminochrysene (chrysen-6-amine) is an aromatic amine research compound supplied in solid and solution formats for biochemical and pharmacological studies. The compound has documented analytical data including purity, molecular formula, and molecular weight, and includes guidance for solubility and storage for laboratory use. Handle and store according to safety data recommendations.
eMolecules 789-47-9 | 2-Aminochrysene | Combi-Blocks, Inc. | MFCD00046286 | 243.309 | C18H13N | 97.000 | Nc1ccc2c(ccc3c4ccccc4ccc23)c1 | 1g | 569291100
2-Aminochrysene | Combi-Blocks, Inc. | 789-47-9 | MFCD00046286 | 243.309 | C18H13N | 97.000 | Nc1ccc2c(ccc3c4ccccc4ccc23)c1 | 1g | 569291100
![Sigma Aldrich Fine Chemicals Biosciences Benzo[c]chrysene BCR(R), certified reference material | 194-69-4 | MFCD00667762 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501759706.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Benzo[c]chrysene BCR(R), certified reference material | 194-69-4 | MFCD00667762 | 100MG
Benzo[c]chrysene BCR(R), certified reference material | Mol Wt: 278.35 | 194-69-4 | MFCD00667762 | 100MG
Apexbio Technology LLC PERYLENE-D12-25MG
Perylene-d12 (CAS No 1520-96-3) is a deuterated chemical compound used primarily in the field of biomedical research as a tracer in mass spectrometry and as a standard for quantitative analysis Derived from perylene its mechanism of action involves intercalation into DNA and interaction with cellular membranes impacting nucleic acid processes Perylene-d12 exhibits potent in vitro activity typically observed in the nanomolar to low micromolar range It is widely used across various cell models and animal studies particularly in drug screening and toxicology assessments Experimental concentrations typically depend on the specific research design
![Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene >=96% (HPLC) | 50-32-8 | MFCD00003602 | 5G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501848405.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene >=96% (HPLC) | 50-32-8 | MFCD00003602 | 5G
Benzo[a]pyrene >=96% (HPLC) | Purity: >=96% (HPLC) | Mol Wt: 252.31 | 50-32-8 | MFCD00003602 | 5G
Apexbio Technology LLC Oxaloacetic acid 328-42-7 200mg
Oxaloacetic acid (CAS 328-42-7) is a small molecule metabolic intermediate involved in multiple biosynthetic pathways including the citric acid cycle It modulates mitochondrial metabolism and has been shown to reduce intracellular reactive oxygen species (ROS) levels thereby attenuating oxidative stress in cells Due to these properties oxaloacetic acid serves as a valuable tool in the investigation of metabolic disorders and mitochondrial dysfunction in biomedical research
Medchemexpress LLC PROTAC BCR-ABL Degrader-1 | C43H40N10O6 | 25 MG
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1) is a PROTAC with a 2-oxoethyl linker. It induces Bcr-Abl degradation in a ubiquitinproteasome-dependent manner and exhibits antiproliferative activity against K562 cells. It has the potential to study cancer.
- Induces Bcr-Abl degradation.
- Exhibits antiproliferative activity against K562 cells.
- Useful for cancer research.
- Features a 2-oxoethyl linker.
Medchemexpress LLC Gabapentin hydrochloride | 60142-95-2 | >98.0% | C9H18ClNO2 | 200 MG
Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. It functions by inhibiting neuronal Ca2+ influx and reducing neurotransmitter release. This compound, which is a GABA analog, can be used to relieve neuropathic pain.
- It is a potent calcium channel blocker.
- It is orally active.
- Inhibits neuronal calcium influx.
- Reduces neurotransmitter release.
- It is a GABA analog.
- Can be used to relieve neuropathic pain.
Medchemexpress LLC Alvespimycin (hydrochloride) | 467214-21-7 | 98.8% | 653.21 | 200 MG
Alvespimycin hydrochloride is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM. It inhibits the growth of human cancer cell lines SKBR3 and SKOV3, which overexpress Hsp90 client protein Her2, leading to down-regulation of Her2 and induction of Hsp70. It also induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells.
- Potent inhibitor of Hsp90
- Binds to Hsp90 with an EC50 of 62 ± 29 nM
- Inhibits the growth of human cancer cell lines SKBR3 and SKOV3
- Causes down-regulation of Her2
- Induces Hsp70
- Induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells
- Significant reduction in tumor size in animal models
Medchemexpress LLC AM095 free acid | 1228690-36-5 | 99.0% | 456.49 | 200 MG
AM095 free acid is a potent LPA1 receptor antagonist that effectively inhibits LPA-induced calcium flux in CHO cells transfected with human or mouse LPA1. It also significantly reduces LPA-induced vasorelaxation and inhibits LPA-driven chemotaxis in various cell types. In preclinical studies, it has shown to attenuate bleomycin-induced dermal fibrosis and decrease kidney fibrosis in a mouse model of unilateral ureteral obstruction. The compound exhibits high oral bioavailability, a moderate half-life, and is well tolerated in animal models.
- Potent LPA1 receptor antagonist.
- Inhibits LPA-induced calcium flux in CHO cells.
- Reduces LPA-induced vasorelaxation.
- Inhibits LPA-driven chemotaxis in melanoma cells.
- Attenuates bleomycin-induced dermal fibrosis in vivo.
- Decreases kidney fibrosis in a mouse model.
- High oral bioavailability.
- Moderate half-life.
- Well tolerated in rats and dogs.